Inositol for sleep

Key Takeaways

Inositol supports sleep by modulating key neurotransmitters. As a secondary messenger in the phosphatidylinositol pathway, myo-inositol influences serotonin and GABA, helpng improve sleep latency, quality, and continuity.
Brain myo-inositol levels are linked to restorative sleep. Lower levels are associated with reduced slow-wave sleep, while supplementation has been shown to improve global sleep quality and duration in clinical trials.
Dosing is typically 1 to 4 grams daily and is generally well tolerated. Monitor for mild gastrointestinal symptoms and use caution in patients taking diabetes medications due to potential additive glucose-lowering effects.

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