Managing irritable bowel syndrome

Irritable Bowel Syndrome (IBS) is a common, often chronic functional gastrointestinal disorder affecting 1 in 7 adults. While its exact cause remains unclear, IBS is increasingly understood as a multifactorial condition involving dysbiosis, gut-brain axis (GBA) dysfunction, visceral hypersensitivity, immune activation, and impaired gut motility and barrier integrity.

The gut and brain communicate bidirectionally via neural, endocrine and immune pathways. Stress, infection, and microbiome imbalances can disrupt this axis, driving inflammation, altered pain perception, mood disturbances, and motility issues. These interactions contribute to the hallmark symptoms of IBS: abdominal pain, bloating, and altered bowel habits.

Emerging research highlights the role of targeted natural interventions that support microbiome balance, gut barrier function, neuromodulation, and inflammation regulation. Key interventions include probiotics like Lab4 and Saccharomyces boulardii, PHGG (partially hydrolysed guar gum), and peppermint oil - each addressing distinct pathophysiological drivers.

This infographic explores the underlying mechanisms of IBS and the science-backed natural agents shown to support symptom relief, mood balance, and improved quality of life through microbiome-GBA modulation.