Chronic pain & central sensitisation

Chronic pain is persistent pain lasting more than 3-6 months.¹ Chronic pain is complex and it is often reported that chronic pain sufferers concurrently experience psychological distress and symptoms such as poor mood and sleep.¹ The body is equipped with a variety of mechanisms and systems to alleviate and resolve pain, including the endocannabinoid system. Compounds such as palmitoylethanolamide (PEA) and Crocus sativus (saffron), have the unique ability to influence the endocannabinoid system and in turn, manage chronic pain and its associated symptoms. Chronic pain sufferers are more likely to experience psychological issues such as depression, anxiety, and sleep disturbances.